EAN: 9781493926268

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Alzheimer's disease (AD) and many other neurodegenerative disorders are multifactorial in nature involving a combination of genomic epigenomic network dynamic and environmental factors. A proper investigation requires new integrative Systems Biology approaches at both the experimental and computational level. The interplay of disease mechanisms and homeostatic networks will underlie the time of onset and rate of progression of the disease.This book addresses such an integrated approach to AD. It aims to present Systems Biology including both experimental and computational approaches as a new strategy for the study of AD and other multifactorial diseases with the hope that the results will translate into more effective diagnosis and treatment as well as improved public health policies.Written for the highly successful Methods in Molecular Biology series practical and cutting-edge Systems Biology of Alzheimer's Disease is intended for post-graduate students post-doctoral researchers and experts in different fields with an interest in comprehensive Systems Biology strategies applicable to AD and other complex multifactorial diseases (including other neurodegenerative diseases and cancers). This book aims to complement other excellent volumes and monographs on AD that cover fundamental physiological or medical aspects of the disease.

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05.04.2025 um 03:25 Uhr

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